Bioelectricity: A Quantitative Approach @ FIX University Campus

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Announcements

New Lectures

• 1. Intro to week 2 (0:38)
• 2. A membrane patch, the idea of it (7:31)
• 3. Energy as trans-membrane Voltage Vm (2:41)
• 4. Sodium-potassium pumps (5:53)
• 5. Ionic equilibrium (13:51)
• 6. Battery lifetime (5:02)
• 7. Problem session 1 (4:13)
• 8. Membrane resistance Rm (10:27)
• 9. Membrane capacitance Cm (4:45)
• 10. Why is Cm so big? (7:38)
• 11. Problem session, R and C (8:19)
• 12. Week 2 summary (5:53)

Duke / Coursera / Bioelectricity Starting Week 2

Today, October 1, marks the beginning of the second week of Bioelectricity. If you are going to be able to focus on the course for just one week, make it this week, Week 2. In this week you will learn how bioelectric systems generate and sustain voltages across the membrane. These voltages function similarly to dry-land batteries in that the voltages are the power sources for electrical circuits. Amazingly the voltage-producing mechanisms are not destroyed by their salt-water environment. Rather, they take advantage of it ! And, as we ourselves demonstrate, they don't fail after a day, a month, or a year --- they last a lifetime. If you do not already know where bioelectric voltages come from, now --- this week --- is your chance. The whole mystery will be unfolded, and by means of your imagination (smile) made visible.

If you are still working on Week 1 --- it is OK. You can continue to do so for another week :)

..rcb

Mon 1 Oct 2012 7:45:00 AM PDT

Why does Bioelectricity"s week roll over when it does?

All my life that I can remember, weeks were given to me on a calendar. One week changed to the next according to when the calendar said it did. It was thus with great delight that I learned that Bioelectricity weeks would end whenever I said they would :) When I asked about the wisdom of various possibilities, people told me that many Coursera students often needed to ---or wanted to--- work on weekends, so it would be better if most students had a whole weekend at the end of each week. Also, it seemed like a good idea if the Bioelectricty week ended during "regular business hours" at Duke, where we are, in case there was some problem that came up during the transition. Putting these factors together, and also learning that the week would be specified to Coursera in Pacific time, the time in California, my choice was to end Bioelectricity's week at noon on Monday, Pacific time. Yes, I know that it does seem strange for a week to end in the middle of a day, and I realize that for most of us it means the week rolls over at a rather odd time, maybe even the wee hours of Tuesday. The good part is that you should have the whole weekend, wherever you are. ..rcb

Sun 30 Sep 2012 10:44:00 AM PDT

Hints & Kinks

"Hints & Kinks" is a new label recently added to the left column. It is a place where I will add additional information about the videos and quiz questions, a place for hints, comments, and background on why things are as they are, and a place to note connections you might not have noticed. Some items will be there in response to your comments and others because I thought you might want to know. For example, I started by talking about the quiz 1 questions. My intention is to make additions every week, so please check from time to time to see what you find there that is useful or interesting. ..rcb

Fri 28 Sep 2012 6:42:00 AM PDT

Scoring Plan

Please note that the details of the scoring plan are now available to you. They are given when you press the link "Scoring Plan" in the list on the left. Please read or review as needed. ..rcb

Fri 28 Sep 2012 6:20:00 AM PDT

Bioelectricity course -- Amazing Beginning, and Thank you to the Assistant Teachers

So far there have been thousands and thousands of you viewing videos, and thousands of responses to the quiz questions. There are still several days to go in Week 1 of Coursera/Duke/Bioelectricity, so I'm sure that many more people will stant the course during this latter half of the week.

To those of you who have done a lot already ==> great start.

To those of you who are beginning now or will soon ==> there is still plenty of time, and you will find an energetic group of colleagues and friends here.

Special thanks to each of you who reach out to others who are trying to do something for the first time or trying to answer a question but seeing it scored as incorrect. I think of you as our Assistant Teachers, and we need you. I know from personal experience how important it can be to do the one thing or answer the one question that is proving a stumbling block to someone.

I think you all have gotten the course off to a very good start. Thank you.

..rcb

Thu 27 Sep 2012 8:05:00 AM PDT

Doing great, and 2 items to come.

You all are doing great! You have moved quickly into the videos and quizzes, more quickly and more intensely than I expected. I love the reading your comments on the discussion forums. I read all of them and enjoy --- or at least learn from -- every one, even though I mostly do not respond.

We are still finishing up some parts of the course organization, and I wanted you to know about two items that will be available to you soon. (1) The first is the scoring plan (how individual scores will be weighted and added). That's taken a little longer than expected because it has to be ok as to concept (me) and ok as to doing it (Coursera system). We will have it for you soon, and I think you will find that it is fine. (2) The second item soon to come is adding a section on "Hints & Kinks" where I will give some hints on the quiz questions, for those who would like them (hints), and identify places in the videos or questions where we discover small glitches (kinks). I'll put in there some notes on how one thing connects to another in ways you may have overlooked. There are a lot of strong but not-so-obvious connections :)

This course is an exciting adventure for me and no doubt for you too. I've taught courses for a long time, but never anything quite like this one :)

..RCB

Wed 26 Sep 2012 5:49:00 AM PDT

Course Wiki now open & New Week 1 Slides!

Hello all,

The Course Wiki for Bioelectricity is now open, at the request of some students! Please note that information posted on the Course Wiki will not be curated or monitored for accuracy and correctness by Professor Barr or myself. Enjoy Wiki-ing!

Also, the Week 1 slides have now been updated to reflect the slides used in the lecture videos. Sorry for the confusion!

-Zack

Tue 25 Sep 2012 6:13:00 AM PDT

Note on precision for quiz answers

For all quiz questions (in this week and others) requiring numerical answers, the required precision for full credit is +/- 1% of the correct exact answer. Hope this clears up everybody's questions!

-Zack (your trusty TA)

Mon 24 Sep 2012 2:59:00 PM PDT

Welcome to Bioelectricity Week 1

Welcome to Bioelectricity Week 1, the first week of this eight-week course. This first week brings some exciting topics such as what happens when you throw your computer in the ocean (smile), and also some fundamentals on the rules of electricity in solutions. Please keep your thoughtful imagination with you at all times. Together we will liberate this fascinating subject from the box in the closet where it has been kept hidden away for the last 200 years :)

The normal sequence of things to do this week is to watch the week's videos and then to answer the week's questions. You are free however to do videos and questions in any order or to go back and forth. You can do the quiz more than one time, and if you do the highest score is the only one that counts. It is up to you to find what works best for the way you think and for your study style. You will, however, get far more from this course by working on the questions than if you simply listen to the lectures. Somehow it is when you try to answer questions that you really engage your brain :)


Please begin this first week of the course by clicking on "Start Here!" near the top in the menu in the column on the left. There you will see step by step instructions telling you what to do next.

Thank you for enrolling. This course will be an adventure, intriguing and productive. Once again, welcome! Let's get started.

Fri 21 Sep 2012 6:19:00 PM PDT

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